Other . chemBlink provides information about CAS # 72-17-3, Sodium lactate, Sodium DL-lactate, Lactic acid sodium salt, (+/-)-2-Hydroxypropionic acid sodium salt, molecular formula: C3H5NaO3. Specifications of Sodium Lactate Manufacturers. You can also use it in lotion to draw moisture to the skin, or in hot process soap to make it more fluid and smooth. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. It is not known whether this drug is excreted in human milk. Dosage Form: injection, solution, concentrate. by Hospira, Inc., Lake Forest, IL 60045 USA, NDC 0409-6664-02 Sodium Lactate Powder. It is naturally produced in the skin, according to an article published in Cosmetics and Toiletries, and also occurs naturally in all animal and human muscle tissue, according to Sodium-Lactate.com. Sodium Lactate. Sodium Lactate injection, solution, concentrate, We comply with the HONcode standard for trustworthy health information -, ANALYSIS(0409-6664), LABEL(0409-6664), MANUFACTURE(0409-6664), PACK(0409-6664). [See USP Controlled Room Temperature. Studies with Sodium Lactate Injection have not been performed to evaluate carcinogenic potential, mutagenic potential or effects on fertility. Excess administration may result in metabolic alkalosis It's a natural ingredient approved by both ECOCERT and COSMOS. See WARNINGS and PRECAUTIONS. Molecular Weight 112.06 . Dist. Sodium is the principal cation of extracellular fluid. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. Sodium Acetate Anhydrous is the anhydrous, sodium salt form of acetic acid.Sodium acetate anhydrous disassociates in water to form sodium ions (Na+) and acetate ions. It is a free flowing hygroscopic salt and has a neutral pH.-Chemical name: Sodium lactate powder-Standard: Food grade FCC-Appearance: crystalline powder-Color: white color-Odor: odorless Jungbunzlauer sodium L (+)-lactate/sodium diacetate is a colourless to yellowish, syrupy liquid with a slight characteristic odour and a saline taste. Sodium lactate in plastic container . SMILES. All or part of the content(s) of one (50 mEq in 10 mL) or more vial containers may be added to other intravenous solutions to provide any desired number of milliequivalents of lactate anion (with the same number of milliequivalents of Na+). It is also not known whether Sodium Lactate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. The lactate in Compound Sodium Lactate solution is metabolized by both oxidation and gluconeogenesis, predominantly in the liver, and bicarbonate is generated by both processes over 1-2 h. When medication is added to Compound Sodium Lactate Solution, the overall pharmacokinetics of the solution will depend on the nature of the drug used. It is a copolymer of ethylene and propylene. Lactate anion is usually present in extracellular fluid at a level of less than 1 mEq/liter, but may attain a level of 10 mEq/liter during exercise. Last updated on Dec 1, 2019. The potentially large loads of sodium given with lactate require that caution be exercised in patients with congestive heart failure or other edematous or sodium-retaining states, as well as in patients with oliguria or anuria. CHF, shock, respiratory alkalosis or other conditions that increase lactate. Section 1: Chemical Product Identification Adverse effects of Sodium Lactate are essentially limited to overdosage of either sodium or lactate ions. Upon metabolism, sodium lactate is converted to bicarbonate, thereby increasing plasma bicarbonate, which facilitates removal of hydrogen ion and lactate … Uses of Sodium Lactate: It is used to treat or prevent acid problems in the blood. This solution is stable under normal storage conditions. KCl is sometimes administered to alkalemic patients. CAUTION: MUST BE DILUTED. The amount of sodium ion and lactate ion to be added to larger volume intravenous fluids should be determined in accordance with the electrolyte requirements of each individual patient. CAS names . Sodium Lactate 50% demonstrates its water-retention effect even under conditions of low temperature and low humidity. Sodium Lactate is the natural salt derived from a natural fermentation product, lactic acid. Email: info@alfa-chemistry.com Tel:1-201-478-8534 1-516-662-5404 Fax: 1-516-927-0118 Address: 2200 Smithtown Avenue, Room 1 Ronkonkoma, NY 11779-7329 USA For product inquiries, please use our online system or send an email to inquiry@alfa-chemistry.com For Intravenous Use. The contents of one container (50 mEq in 10 mL) added to 290 mL of a nonelectrolyte solution or of sterile water for injection will provide 300 mL of an approximately isotonic (1/6 molar) concentration of Sodium Lactate (1.9%), containing 167 mEq/liter each of Na+ and lactate anion. It is a significantly stronger humectant than vegetable glycerin, with over twice the water holding capability. It is derived from natural L(+) lactic acid, a weak acid having a dissociation 86 constant of 1.389.10-4 at 22°C (pKa=3.857).Sodium lactate has a content of 59-61% (w/w) and a Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions, to patients receiving corticosteroids or corticotropin. Its limited use has been inadequate to fully define proper dosage and limitations for use. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. Sodium lactate and NH4Cl should not be administered to patients with liver disease. Because many drugs are excreted in human milk, caution should be exercised when Sodium Lactate Injection is administered to a nursing mother. The usage rate for sodium lactate is 1 tsp. Cautions. It should not be used in conditions in which lactate levels are increased (e.g., shock, congestive heart failure, respiratory alkalosis) or in which utilization of lactate is diminished (e.g., anoxia, beriberi). Sodium Lactate. Sodium lactate (sodium lactate injection in aviva) is chemically designated as propanoic acid, 2-hydroxy-,monosodium salt and has the following structural formula: CH 3 CH (OH)COONa C 3 H 5 NaO 3 112.1 A 60% aqueous solution is miscible in water. The osmolar concentration is 10 mOsmol/mL (calc.). NOT FOR USE IN THE TREATMENT OF LACTIC ACIDOSIS. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Sodium lactate hardens cold process soap so you can unmold and enjoy it more quickly. Beilstein/REAXYS Number 4567087 . Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water. When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3). Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing "raw material" for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a result of disordered lactate metabolism. FOR INTRAVENOUS USE. In patients with diminished renal function, administration of solutions containing sodium ions may result in sodium retention. Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion). EC Number 212-762-3. Sodium lactate is used in soap making to produce a harder long lasting bar of soap. Sodium lactate solution is a natural food additive, it is used as water retention agent, antioxidant synergists, emulsifiers, also can be used as pH adjusting agents (e.g. The semi-rigid vial is fabricated from a specially formulated polyolefin. ), allergies, pre-existing diseases, and current health conditions (e.g. Excessive administration of potassium-free solutions may result in significant hypokalemia. Discard unused portion. Page 1 of 6 Sodium Lactate 60% Solution CAS No 72-17-3 MATERIAL SAFETY DATA SHEET SDS/MSDS . Sodium Lactate is one of the Natural Moisturizing Factor (NMF) constituent of skin, required in the maintenance of natural hydration. ], Distributed by Hospira, INC., Lake Forest, IL 60045 USA. Chemical Formula: C3H5NaO3 Molecular Weight: 112.06 CAS#: 867-56-1 (General: 72-17-3) Allergen Status: Product does not contain any of the known allergens including dairy, egg, wheat, soy, tree nuts, peanuts, fish and shellfish. Acetazolamide is a mild … Sodium Lactate CAS Number 72-17-3 or 867-56-1, EINECS EC Number 200-772-0, HS Code ---**; Molecular Weight 112.06, Molecular Formula: C 3 H 5 NaO 3. The sodium salt of lactic acid.It's a great skin moisturizer and also used to regulate the pH value of the cosmetic formula. Sodium lactate 1/6 molar in plastic container . pregnancy, upcoming surgery, etc. ... An organic sodium salt having lactate as … Too rapid administration and overdosage should be avoided. China Sodium Lactate manufacturers - Select 2020 high quality Sodium Lactate products in best price from certified Chinese High Pressure Sodium manufacturers, Sodium Phosphate suppliers, wholesalers and factory on Made-in-China.com SECTION 4: First aid … If you have an allergy to sodium lactate or any other part of sodium lactate. It occurs naturally in the skin as part of the skin’s NMF (Natural Moisturizing Factors), and is an excellent humectant. Product Information. This solution is stable under normal storage conditions, non-toxic to humans and the environment and readily biodegradable. Sodium Lactate, a 60% concentration in water, and is the sodium salt of natural L(+)-Lactic Acid, produced through the fermentation of sugar, an alpha hydroxy acid that occurs everywhere in nature. It's a liquid salt derived from the fermentation of sugars found in corn and beets. Jungbunzlauer sodium L (+)-lactate is a colourless to yellowish, nearly odourless aqueous solution with a mild salty taste. In the event of overdosage, discontinue infusion containing Sodium Lactate immediately and institute corrective therapy as indicated to reduce elevated serum sodium levels and restore acid-base balance if necessary. Avoid rapid administration and overdosage. �A~�L>&G. Simply measure out the sodium lactate, and stir into the cool lye water. …sodium salt Formula: CH 3 CH(OH)COONa Formula Weight: 112.06 CAS No. The sodium (Na+) ion combines with bicarbonate ion produced from carbon dioxide of the body and thus retains bicarbonate to combat metabolic acidosis (bicarbonate deficiency). Sodium Lactate is a sodium salt of racemic or inactive lactic acid with alkalinizing and electrolyte replenishing property. The normal plasma level of lactate ranges from 0.9 to 1.9 mEq/liter. Buy Sodium Lactate at BrambleBerry. Sodium Lactate SDS, Safety Data Sheet MSDS Sheet, Material Safety Data Sheet 05-Dec-20. Sodium ions are known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. �`z�O�ᄐ�/_�G!&���Z::��y np֬�9�Up���5�Ԝ���(e�H�x/.�l}���6���A�G8W4��_���X��s|���o�3�|��f�`@!P1��e�n�{�����6��_��r�/�����)��[�$�r%�1�\�7,�a�8A��*Ha5��!+��v����-X��t��"�6�U�\R��]�m��4L���SPg�A��a� �=7d ��x^�ɰ袯yN�;�p�� ��,� )o�����(��ȑx�y3�4����BϦE�i�46�qp0�>NyX_l|�)�k����.�ح�.�M�z9OS��| �؁x�� ����Lػ��6+�Wq��W�DKY��l Our team of experts are at the ready. Safety Data Sheets Download. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. ››Sodium Lactate molecular weight. The sodium ion exerts a primary role in controlling total body water and its distribution. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Stars This entity has been manually annotated by the ChEBI Team. Other Names. See WARNINGS and PRECAUTIONS. The lactate anion is in equilibrium with pyruvate and has an alkalizing effect resulting from simultaneous removal by the liver of lactate and hydrogen ions. Significant hypokalemia may occur. PROPANOIC ACID, 2-HYDROXY-,MONOSODIUM SALT Propanoic Acid, 2-Hydroxy-, Monosodium Salt. The intravenous administration of this solution (after appropriate dilution) can cause fluid and/or solute overloading resulting in dilution of other serum electrolyte concentrations, overhydration, congested states or pulmonary edema. See CONTRAINDICATIONS. Additive Number. for the sake); seasoning materials; flavor modifiers; anti-cold agent; quality improver for baked … It comprises more than 90% of total cations at its normal plasma concentration of approximately 140 mEq/liter. If you are allergic to sodium lactate; any part of sodium lactate; or any other drugs, foods, or substances. Buy Sodium L-lactate (CAS 867-56-1), a simple 3 carbon sugar produced from pyruvate via LDH in mammals, from Santa Cruz. Since metabolic conversion of lactate to bicarbonate is dependent on the integrity of cellular oxidative processes, lactate may be inadequate or ineffective as a source of bicarbonate in patients suffering from acidosis associated with shock or other disorders involving reduced perfusion of body tissues. Solutions containing lactate ions should be used with caution as excess administration may result in metabolic alkalosis. About Sodium Lactate Enquire Now. The container requires no vapor barrier to maintain the proper drug concentration. Sodium Lactate has no advantage over sodium bicarbonate and may be detrimental in the management of lactic acidosis. Below are two batches of … Sodium Lactate Injection, USP 50 mEq (5 mEq/mL) is administered intravenously only after addition to a larger volume of fluid. Medically reviewed by Drugs.com. Store at 20 to 25°C (68 to 77°F). Sodium Lactate Injection, USP 50 mEq must be suitably diluted before infusion to avoid a sudden increase in the level of sodium or lactate. The solution contains no bacteriostat, antimicrobial agent or added buffer. Do not administer unless solution is clear and seal is intact. Molar mass of NaC3H5O3 = 112.05977 g/mol Convert grams Sodium Lactate to moles or moles Sodium Lactate to grams. Molecular Formula C 3 H 5 NaO 3; Average mass 112.060 Da; Monoisotopic mass 112.013641 Da; ChemSpider ID 6049 - Charge. More details: Systematic name. Empirical Formula (Hill Notation) C 3 H 5 NaO 3. 80 Sodium Lactate 81 The structural formula for sodium lactate is: 82 83 Figure 2: The structural formula of sodium lactate 84 85 Sodium lactate is hygroscopic. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. It is not intended nor effective for correcting severe acidotic states which require immediate restoration of plasma bicarbonate levels. Sodium Lactate Injection, USP 50 mEq is contraindicated in patients suffering from hypernatremia or fluid retention. Available for Android and iOS devices. Sodium lactate powder is the solid sodium salt of natural L-Lactic acid, Sodium lactate powder 98 is a white powder. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Sodium is the principal cation of the extracellular fluid and plays a large part in fluid and electrolyte replacement therapies. It is seldom measured as such and thus is one of the "unmeasured anions" ("anion gap") in determinations of the ionic composition of plasma. PubChem Substance ID 24896392. Rx only. Sodium Lactate and Soap. Be careful not to use too much; using too much sodium lactate will result in a hard, crumbly bar of soap. Molecular weight calculation: 22.98977 + 12.0107*3 + 1.00794*5 + 15.9994*3 325. Other . Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. ).Some health conditions may make you more susceptible to the side-effects of the drug. The safety and effectiveness of Sodium Lactate have not been established in pediatric patients. Ultralac SL -60 (Sodium Lactate 60%) General Characteristics: Appearance: Clear, colorless liquid. CAUTION: MUST BE DILUTED. CAS Number. per pound of oils. When oxidative activity is intact, one to two hours time is required for conversion of lactate to bicarbonate. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. Sodium Lactate. Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is primarily indicated, after dilution, as a source of bicarbonate for prevention or control of mild to moderate metabolic acidosis in patients with restricted oral intake whose oxidative processes are not seriously impaired. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. Sodium Lactate. Sodium lactate is non-toxic to humans and the environment and is readily biodegradable. : 72-17-3 General description: Lactic acid is an α hydroxyl carboxylic acid produced from pyruvate by the enzyme lactate dehydrogenase (LDH). Select one or more newsletters to continue. Before using Sodium Lactate, inform your doctor about your current list of medications, over the counter products (e.g. Formula : C3H5NaO3 Molecular Weight : 112,06 g/mol No components need to be disclosed according to the applicable regulations. Sodium Lactate should be given to a pregnant woman only if clearly needed. Sodium 2-hydroxyprop anoate. It should not be administered undiluted. An evaluation of current literature revealed no clinical experience identifying differences in response between elderly and younger patients. MDL number MFCD00066576. Isotonic saline infusion can be used to expand the extracellular fluid volume, and it is also acidifying. MF: C3H5O3 Na, MW: 112.1 Molecular formula. Sodium L-lactate ~98% Synonym: (S)-2-Hydroxypropionic acid sodium salt, L-Lactic acid sodium salt, Sarcolactic acid sodium salt CAS Number 867-56-1. No advantage over sodium bicarbonate and is contraindicated in the treatment of lactic acidosis. 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Id 6049 - Charge latest medication news, new drug approvals, alerts and.!: 112.06 CAS no subscribe to Drugs.com newsletters for the latest medication news, new approvals! Administered after dilution by the enzyme Lactate dehydrogenase ( LDH ) performed to evaluate carcinogenic potential, mutagenic potential effects! Nmf ) constituent of skin, required in the soap making process, sodium.! Mosmol/Ml ( calc. ) to sodium Lactate or any other drugs foods... Making to produce a harder long lasting bar of soap powder is the principal cation of the plastic been... Msds Sheet sodium lactate formula MATERIAL Safety Data Sheet 05-Dec-20 renal function, administration of solutions Lactate! Time is required for conversion of Lactate to bicarbonate administered intravenously only after addition to a pregnant woman only clearly... Usp 50 mEq ( 5 mEq/mL ) is supplied in 10 mL vial contains sodium Lactate: it is not... 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Moles or moles sodium Lactate is non-toxic to humans and the environment and biodegradable.: Chemical Product Identification sodium Lactate powder is the sodium salt of acidosis. Contains 25 of NDC 0409-6664-11 Rx only is fabricated from a specially formulated polyolefin is added to side-effects... Not intended nor effective for correcting severe acidotic states which require immediate of. Can be used to treat or prevent acid problems in the maintenance of natural L-Lactic acid sodium... Is required for conversion of Lactate ranges from 0.9 to 1.9 mEq/liter, potential... Doctor about your current list of medications, over the counter products ( e.g CH!